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As well, mutating Apos refrains atherosclerotic development through lessening LDL retention

Thus, lysosomal processing is essential for efficient removal of toxic cellular components [146, 148]

These findings provide a molecular-level explanation for how systemic immune dysregulation in PFCD impacts amino acid metabolism and how localized infection in CAF elicits distinct metabolic perturbations, thus highlighting potential targets for future research and intervention