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Moreso, enhanced survival of the ERCC mutant cohort in response to ICI administration was observed in comparison with non-mutant ERCC cohorts

1 plays an important role in arsenic uptake and root-to-shoot translocation under arsenite stress conditions

In Control cells, nutlin-3 treatment down-regulated numerous genes involved in nucleotide metabolism, including DTYMK , CTPS1 , RRM1 , and RRM2 (Fig 3B)