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Mechanistically, DAMPs interact with toll-like receptors (TLRs) and purinergic receptors on Kupffer cells, resulting in the secretion of pro-inflammatory mediators such as IL-6, IL-18, IFN-, TNF-, and Fas ligands, which further promote macrophage proliferation [54]

These antioxidants, in combination with Glutathione, help protect the skin from environmental damage, slow down the aging process, and promote skin rejuvenation

However, there are insufficient studies on curcumin cooperating with the sestrin family to inhibit tumors, and the mechanism is still unclear

Glutathione is an antioxidant that is produced naturally by the liver