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doi: 10.31887/dcns.2009.11.3/mbelanger, 31

Considering the fact that tumour microenvironment stresses are strong inducers of the endoplasmic reticulum stress (Murakami et al, 2007), the FASN inhibitors could show selective and enhanced cytotoxicity to cancer cells under the tumour microenvironment conditions

If offering peptides outside approved indications, clinicians should present use as experimental, disclose regulatory status and paucity of clinical studies, describe known and unknown risks, and outline standard treatment alternative (e.g

Patients returning to activities they had been avoiding due to pain or limited function