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Percent homolysis was then graphed as a function of OD600

Moreover, spermidine inhibits histone acetyltransferase p300 (EP300), a protein that suppresses autophagy, thereby enabling the activation of autophagy-related genes (Atg) (Reference Madeo, Carmona-Gutierrez and Kepp18)

These include redox cycling that enhances oxidative stress through Fenton-like reactions, leading to lipid peroxidation and nucleic acid damage (Warnes et al., 2012