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Vitamin B12 is necessary for red blood cell production, energy metabolism, and the conversion of propionate to glucose during exercise, contributing to normal stamina and metabolic function

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These compounds may ameliorate misfolded protein aggregation, neuroinflammation, and high glucose levels linked to oxidative stress during brain aging [156, 194]

For example, the abundance of cellular indole, adenosine monophosphate, and nutrient metabolites influences transmembrane proton motive force (PMF), drug and nutrient uptake, and bacterial survival in the presence of antibiotic drugs