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According to meta-analysis data, hypothyroidism occurs in about 3.8% of patients treated with anti-CTLA-4, 3.9% with anti-PD-L1, 7.0% with anti-PD-1, and 13.2% with combination therapy

Copper transporters and copper chaperones: roles in cardiovascular physiology and disease

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In referring to sequences, the terms "native" or "reference" are relative terms referring to the original molecule to which a comparison may be made