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This non-specific action can also interfere with the physiological signaling roles of ROS (as discussed in Section 2.2), potentially leading to unintended adverse effects or a lack of targeted efficacy

doi: 10.1038/nature14363 46 Ben-SahraIHoxhajGRicoultSJHAsaraJMManningBD

By the time oral glutathione reaches your small intestine, its been disassembled into its three individual amino acids glutamate, cysteine, and glycine