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Autophagy, which induces the degradation and recycling of long-lived proteins or organelles, can be directed by ROS and so with being indirectly regulated by antioxidant systems

10.1371/journal.ppat.1002540 126 KlionskyD

AONs are readily available through solid-phase oligonucleotide synthesis and therefore represent an ideal starting point for most oligonucleotide conjugations