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ET 50 is the treatment duration to reach half of E max

Nevertheless, by testing compounds that targeted different stages of the ferroptosis pathway in different ways, and finding that they could all rescue altered A42-induced larval crawling behaviour, we conclude that inhibition of ferroptosis plays a central role in this rescue

Keshavarz ShahbazSKoushkiKKeshavarz HedayatiSMcCloskeyAPKesharwaniPNaderiYet al

This continuous signaling contributes heavily to the neuroinflammation that patients experience as "brain fog," cognitive impairment, and severe mood fluctuations