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10.3389/fendo.2019.00080 33 DepommierC.EverardA.DruartC.PlovierH.Van HulM.Vieira-SilvaS.et al (2019)

Previous studies pointed that astrocytic -synuclein deposition initiates the recruitment of phagocyte microglia that attacks and kills neurons in restricted brain regions [7,19], correlating this -synuclein accumulation with nigral neuronal cell death [20], and suggest the importance of astrocytes in the initiation of the disease