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SKU: 46807961858
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Description

okal BG, Yurtda M, Gler SK, Gne HN, Uar CA, Ayta B, et al

This activation is mediated by the binding of phosphatidylinositol (3,4,5)-trisphosphate (Ptdlns(3,4,5) P 3 ) to the Pleckstrin homology (PH) domain of mSIN1, which relieves its autoinhibition and enables mTORC2 to phosphorylate and activate AKT (Kim and Guan, 2019