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The interplay among iron accumulation, oxidative stress, and neuroinflammation can create vicious cycles that reprogram cellular metabolism and disrupt the critical metabolic coupling between neurons and glial cells

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In lupus-prone mice, 4-PBA reduces splenomegaly, anti-dsDNA antibodies, and inflammatory cytokines and alleviates lupus nephritis by decreasing albuminuria, renal inflammation, and immune complex deposition

A coarsely ground diet reduced the ulcer score in pigs