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Free T4 (Thyroxine): The inactive form of thyroid hormone

Although experimental models clearly establish the importance of the mitochondrialysosome axis in AP pathogenesis, variability in AP induction protocols, limitations of current autophagy and mitophagy assays, and the lack of successful clinical translation of autophagy-targeted interventions underscore the need for more refined, pancreas-specific, and temporally resolved approaches before this system can be exploited therapeutically in patients

In liver Kupffer cells, ATF6 also mediates the pro-inflammatory enhancement of TLR4 response and cytokine production (158)

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