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N-terminal tau truncation in the pathogenesis of Alzheimers disease (AD): Developing a novel diagnostic and therapeutic approach

CHO-WT, CHO M12, CHO M12-A6ko and SH-SY5Y cells were grown in DMEM/F12, NPC1 patient and control fibroblasts were grown in DMEM, together with 10% FCS, L-glutamine (2 mM), penicillin (100 U/ml) and streptomycin (100 g/ml) at 37 C, 5% CO 2

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The occurrence of MACEs, cardiovascular disease mortality, and total mortality was decreased in liraglutide-treated subjects