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doi: 10.1007/s13760-013-0223-5, PMID: [DOI] [PubMed] [Google Scholar] Murakami R., Watanabe H., Hashimoto H., Kashiwagi-Hakozaki M., Hashimoto T., Karch C

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In the context of treatment of menopausal symptoms, relief of symptoms and improvement in quality of life is the primary metric for monitoring hormone therapy

Briefly, GSEA is a computational methodology designed to determine if a defined set of genes has concordant differences between two biological conditions by estimating the significance of the over-representation of an independently defined set of genes in the highly correlated or anti-correlated genes in the ranked list between the two conditions