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Hylemon 1 , Jiangao Fan 2 , Sayed Obaidullah Aseem 3 , Arun Sanyal 3 and Huiping Zhou 1 , (1)Department of Microbiology and Immunology, Medical College of Virginia and Mcguire Veterans Affairs Medical Center, Virginia Commonwealth University, Richmond, VA, (2)Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China, (3)Department of Internal Medicine and GI Division, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298, USA Background: Nonalcoholic fatty liver disease (NAFLD) is the fastest-rising cause of end-stage liver disease for liver transplantation