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Description

Licochalcone a suppresses the proliferation of osteosarcoma cells through autophagy and ATM-Chk2 activation

Information deriving from such disparate fields as earth and environmental sciences, biomedicine, biochemistry and chemical biology, physical chemistry is employed to the aim of building as comprehensive as possible framework to understand the toxic properties of the metals based on the unifying mechanism(s) of their interaction with biologically crucial thiolate ligands