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To target this pathway, chimeric infliximab and fully human adalimumab can neutralize free TNF- and induce apoptosis of TNF--expressing cells, significantly improving symptoms, promoting mucosal healing, and reducing surgery/hospitalization rates [291,292,293,294]

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Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions