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While the bone marrow and hematopoietic cells are most affected, other organs involved in hematopoiesis, such as the thymus and spleen, also sustain injury due to IR [64, 65]

Pallav Sengupta, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The N-terminal residues of the A chain are conserved among vertebrate insulins and have been extensively investigated for their relevance in ligand receptor interactions

Neurology , 50 (2), 466470