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This recommendation, which has since been updated in the GOLD 2023 Report [29], was based primarily on the evidence available for each mucolytic agent at that time

C-terminal turn stability determines assembly differences between Abeta40 and Abeta42

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85 On the other hand, the increase in nitrosylation of Cys166 and Cys131 in the ER thiol oxidase Ero1 leads to a decrease in oxidase activity with aging, stimulating ER reductive stress