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Kehr, S., Sturm, N., Rahlfs, S., Przyborski, J

reported in 1975 that mitochondrial clearance during reticulocyte maturation is initiated by enzymatic lipid peroxidation.20 These authors purified the enzyme 15-lipoxygenase from rabbit reticulocytes and showed that it oxidizes polyunsaturated fatty acids in mitochondrial membranes as an initiating event in the disposal of mitochondria