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10.7759/cureus.70435 122 NishidaY.KamataniN.MiyamotoT

Hemoglobin 2011;35(1) 67-79 55

EVs of ADSCs origin up-regulated the gene expression of glutamine synthetase in hepatocytes while down-regulating the expression of GLS2, which interfered with glutamine metabolism as well as the progression of hepatic fibrosis [129]