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However, ApoE was not adsorbed on uncoated nanoparticles or nanoparticles coated with poloxamer 338 and 407, Cremophor EL or Cremophor RH40

However, this alteration was identified as a passenger epigenetic event, as VIM promoter hypomethylation and mRNA overexpression were linked to the epithelial-to-mesenchymal transition (EMT) of cancer cells, contributing to aggressiveness and disease progression [244]