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Journal of Applied Biology and Biotechnology, 6 (6), 7986

Researchers found that when they plotted prostate DNA damage (antioxidant measure) against toenail selenium status (nutrient concentration or intake) that it resulted in a U-shaped curve like the one shown above1

Int J Neuropsychopharmacol 9(1):101124 Savini L, Gaeta A, Fattorusso C, Catalanotti B, Campiani G, Chiasserini L, Pellerano C, Novellino E, McKissic D, Saxena A (2003) Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites