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To accomplish the decoding of UGA as a SeCys residue, the presence of conserved cis (SECIS elements and the in-frame UGA codon) and trans (SPS1, SPS2, SecS, PSTK, eEFsec, SBP2 and the Sec-tRNA[Ser]Sec)- acting factors is required

Biochemically, LCD proceeds upon LMP when cells are exposed to various lysosomotropic detergents (e.g., lipid metabolites (phosphatidic acid, sphingosine), ROS), including cathepsins [178,179,180,181] (Fig

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After a saturation period of 20 min at room temperature, the plates were meticulously handled to the glass jar and permitted to experience a linear ascending progression of the developing system for a distance of 9.0 cm