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Physiology 447, 752755

Application of a proton beam turned out, consequently, to be an effective mode of therapy of melanotic tumors of the eye (uveal melanoma) (153, 154), and inhibition of melanogenesis (e.g., by the inhibition of tyrosinase activity via sequestration of copper) or increase in oxygen level became a promising way to sensitize melanoma tumors for radiotherapy (152, 155)

More information on how MitoXpress-Extra allows microplate-based analysis of mitochondrial function through the quantitation of oxygen consumption is available in the MitoXpress-Xtra blog from BMG LABTECH

The other angiogenic factors orchestrate the endothelial membrane receptors in GBM, which stimulate a multitude of signaling cascades that result in the proliferation, migration, and differentiation of cells needed to form new blood vessels and matrix formation (Keunen et al