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The excessive NK cell apoptosis induced by pyocyanin may have serious implications for immune function, potentially leading to reduced immune surveillance and responsiveness

After 8 weeks of treatment period, the addition of Astragalus decoction significantly reduced scores on the Unified Parkinsons Disease Rating Scale (UPDRS) Part III and the Parkinsons Disease Quality of Life Questionnaire (PDQ-39) compared to levodopa monotherapy

ROS-induced Lon enhances downstream signaling through the NF-B axis, accelerating tumor progression 70 .The expression of mitochondrial Lon protease is directly regulated by the NF-B signaling pathway 66,71

Despite advances made in CPB immunotherapy in cancers, some issues need to be solved