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GHK-Cu, a tripeptide complex naturally found in the human plasma, is composed of glycine, histidine, and lysine bonded with copper

If these conditions are not treated, TD may spread from the gastrointestinal system to other tissues, as observed in metronidazole-induced encephalopathy (159)

Therefore, we conclude that 5FU promotes metabolic reprogramming in drug-tolerant cells, increasing mitochondrial activity supported by an acute increase in metabolic gene transcription

Also, it has been found that hypertensive patients have low concentration of GSH and high level of GSSG, and the antihypertensive therapy reduced oxidative stress [143]