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Novel propargyl-linked bisubstrate analogues as tight-binding inhibitors for nicotinamide N -methyltransferase

Phytonanoparticles serve as low-toxicity delivery systems that encapsulate active phytochemicals, masking unpleasant tastes, and odors while protecting sensitive compounds from degradation and enhancing bioavailability and therapeutic efficacy [139]

Chronic hyperglycemia-induced ROS overproduction, primarily derived from mitochondrial ETC leakage and NOX activation, leads to eNOS uncoupling due to BH4 oxidation, reducing NO bioavailability and impairing vasodilation (Giacco and Brownlee, 2010)

Research suggests glutathione may shift melanin synthesis toward pheomelanin, a lighter pigment type, instead of eumelanin, which produces darker tones