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The author Z-BJ declared that they were an editorial board member of Frontiers, at the time of submission

Ilustrativo de un pptido de activacin FX es el pptido de activacin de 52 restos de aminocidos en el extremo N de la cadena pesada del polipptido de FX maduro que corresponde a los restos de aminocidos Ser143 a Arg194 en la SEQ ID NO:134.As used herein, an "activation peptide" refers to a segment present at the N-terminus of the FX heavy chain that functions to suppress proteolytic activity by masking the catalytic machinery and thereby preventing the formation of the catalytic intermediate ( that is, conformationally occluding the substrate binding site)

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