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2.7 Data analysis 2.7.1 Concentration and time-dependent response analysis and in vitro PoD determination Concentration and time-dependent changes in the bioactivity readout data were analyzed using a nonlinear state space model, based on the work of Svensson and Schn (2017)

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Meanwhile, PSPH also promotes serine metabolism to generate SAM and GSH

ROS production is exacerbated by reduced protein synthesis, an increase of protein folding capacity, and removal of misfolded proteins, resulting in the accumulation of iron, all of which provide the necessary conditions for ferroptosis (Han et al., 2013)