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When NaBPC157 was given 10 minutes after the application of the combination of L-NAME + L-arginine (still led to a blood pressure increase), its clear effect (noted in L-NAME treated rats) disappeared

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10.3390/agriculture12010015 5 ChenY.LuZ.FengJ.ChenZ.LiuZ.WangX.et al (2023)

However, chronic cases involving ligament laxity typically persist unless the underlying instability is directly addressed