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Interestingly, an in vitro study has demonstrated that nanoemulsified particles of CUR or PPR exhibit greater efficacy compared to their free forms when used in cancer cell lines (34)

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In fact, although acetaminophen is primarily metabolized by the liver, it is also distributed and metabolized in the brain, affecting the balance between antioxidants and oxidative stressors in the brain (Vigo 2019)

UPR-driven tumor dormancy and therapeutic resistance Beyond its role in active tumor growth, the UPR plays a pivotal role in cancer cell dormancy, long-term survival, and resistance to anticancer therapies