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Mohave County, Arizona is identified as a high priority area, being in the top 5% of United States counties at risk for a HCV outbreak, with an average annual rate of 211 new cases per 100,000 people (2017-2021), but lacks traditional access to HCV care due to the rural health disparities of distance to care, lower median income, and lack of healthcare providers

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While autophagy was originally activated as a compensatory response to the cytotoxic stress, extended exposure and elevated dosages led to apoptosis and necrosis

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