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Protoplasma 2012;249:871886.ArticlePubMedPMC 68

This process subsequently triggers lipid peroxidation and ferroptosis, events that cumulatively attenuate the antitumor immune response and reduce the efficacy of immunotherapy

Avoid in patients with peptic ulcers or renal impairment

When comparing the prefusion and postfusion conformation, several structural changes in the domains are evident, alongside the rearrangement of the individual domains as a whole (Fig