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Scientific studies show daily B12 injections of 12 milligrams can quickly fix deficiencies, and routine monthly injections of 1 milligram lower homocysteine levels reducing stroke and heart disease risk

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Together with B-vitamin fortified food (e.g., cereal, nutritional yeast) and supplements, these foods might contribute, though modestly, to prevent vitamin B 12 deficiency in individuals consuming vegetarian diets

(Qiu et al., 2023) reported low levels of NAD + in the aorta from hypertensive patients showing that supplementation with NAD + precursors effectively lowered blood pressure and improved impaired vascular function in both hypertensive patients and mice