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TRPM4 is activated by increased intracellular ATP concentration and oxidative stress, but it is inhibited by intracellular ATP depletion (Nilius et al., 2004

L-Carnitine is naturally produced in the body and is also found in foods, especially animal-derived foods

For instance, the PTEN protein and cytosolic TP53 bind to G6PD to prevent the assembly of G6PD monomers into active dimers and thus decease the PPP flux