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Although this very low glutathione concentration in the apoplast may not be sufficient to act as antioxidant, such as during biotic stress (fungal infection), glutathione and/or its redox state may alternatively have a defense-signaling function in this cell compartment (Zechmann 2020)

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In one case-control study, colonic lavage analytes as markers of mucosal inflammation were compared between healthy dogs and dogs with biopsy-confirmed idiopathic IBD ( Several other studies have investigated serum biomarkers of OS in dogs with CIE at diagnosis and in response to medical treatment

New information even suggests that the parental nutritional state can impose epigenetic metabolic changes in the fetus (49)