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Arterioscler Thromb Vasc Biol 17 : 18941900

FIGURE 3 The immunopharmacological effects of GSH are evident through several distinct but interconnected pathways, including regulation of inflammatory signaling networks like MAPK and NF-B, buffering of pathologic ROS as well as maintenance of cellular ROS signaling, and modulation of both peripheral and central immune cell activity (Peterson et al., 1998)

Maintaining a high pH will maintain the negative charge on both the nucleic acid and the beads

They demonstrated how neuronal debris, including tau in extracellular vesicles, is released when microglial activity is altered in the latter stages of AD