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Clinical side effects leading to discontinuations from these studies were most commonly gastrointestinal (abdominal pain, nausea, vomiting, diarrhea), and rashes

Hyperammonemia induces astrocytic dysfunction, brain edema, and neuroinflammation, while systemic inflammation, oxidative stress, sarcopenia, gut dysbiosis, and altered microbial metabolites, including bile acids and short-chain fatty acids, further modulate disease expression

For others, especially those sensitive to internal changes, the early transition can temporarily influence mood, sleep patterns, and nervous system activity

Safe dosages are: Children: 65 mg/kg/day for six months Teenagers: 20 and 40 milligrams per kilogram of body weight for 3 to 6 months