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Initiation and Propagation of -Synuclein Aggregation in the Nervous System

In our hypothetical model, shown in Figure 5 , the decrease in CAT activity might have resulted in ROS accumulation, leading to lipid peroxidation and enzyme inactivation, which could in turn promote structural and functional damage to proteins and carbohydrates and modification or disruption of DNA structure ( Figure 5 Our study has demonstrated the potential of fungal allelochemicals in inhibiting weed growth through oxidative damage, contributing valuable insights to the limited literature on this topic

In a recent pilot study, patients with T1DM were administered by one dose of 1 10 6 /kg allogenic adipose tissue-derived stromal/stem cells (ASCs) and cholecalciferol 2000 UI/day for 6 months and compared with controls [56]

In some cases, doctors may recommend lifestyle changes alongside medical treatments, such as avoiding prolonged sitting or standing, which can exacerbate symptoms