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The accumulation of mtDNA in the cytosol results in an antiviral immune response, and the oxidation of mtDNA and cardiolipin leads to the activation of the inflammasome that ultimately induces a pro-inflammatory response that should resolve in time (Kelley et al., 2019

Focus paradoxes: Difficulty concentrating on mundane tasks or in quiet settings, yet sometimes experiencing hyperfocus during a crisis or under last-minute deadlines

10.1016/j.amjms.2023.04.034 136 YaoD.BaoL.WangS.TanM.XuY.WuT.et al (2024a)

Other proposed mechanisms include direct interaction with cell surface integrins (particularly alpha-2-beta-1), effects on iron metabolism through copper-iron regulatory interactions, and epigenetic modifications