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4 Both MMA and homocysteine levels will accumulate in the body during B12 deficiency and just homocysteine is elevated for folate deficiency

However, reduction of NO bioavailability, due to the increased oxidative stress state caused by SARS-CoV-2-elevated superoxides, results in the formation of peroxynitrites (ONOO-)

Additional pharmacological effects include enhancing LDL uptake, reducing protein prenylation, improving endothelial function, modulating inflammation, preserving plaque stability and inhibiting thrombosis [922]

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