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In cardiovascular disease, ferroptosis contributes to IRI, where blood flow restoration following ischemia triggers iron influx and the generation of ROS, leading to ferroptotic cell death (97)

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doi: 10.1016/j.radphyschem.2019.108492

Domain 3 Exogenous co-exposures from fuel sources and environment: Contaminants introduced not by the food itself but by the processing environment, particularly heavy metals (lead, cadmium, arsenic, mercury), persistent organic pollutants (dioxins, furans, PCBs, brominated flame retardants), and additional PAH congeners derived from inappropriate fuel sources such as discarded tires, used motor oil, and plastic waste (13, 14)