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Drug Interactions Drug interactions show low risk with most medications but notable considerations include: Zinc supplements: Compete with copper absorption, may affect copper metabolism and GHK-Cu efficacy Birth control pills: Can affect copper metabolism and levels Certain antibiotics: Some may affect copper absorption/utilization Copper-chelating medications: Directly antagonistic to GHK-Cu, should not be used concurrently Copper Overload Realistic Assessment Theoretical concerns about copper toxicity contrast sharply with actual risk at recommended doses