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thus, any crucial alteration of protein structure/activity is fundamental to understanding how molecular events translate into clinical phenotypes

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Hormones (Athens) 20, 35-47 (2021)

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Conversely, NF-B inhibits Nrf2 (261, 262), creating a specific double-negative regulatory system that enhances either the oxidative-inflammatory or antioxidant state, depending on which regulatory scale prevails

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