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Tendons and ligaments have less robust blood supply than muscle, which can make recovery more prolonged

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This term can be used for manic, hypomanic or depressive episodes in bipolar spectrum (type I and II) and major depressive disorders (MDD), characterize by the co-occurrence of three or more manic/hypomanic symptoms in a depressive episode or three or more depressive symptoms in a manic/hypomanic episode [6]

More importantly for the tachyphylaxis question, a single snapshot emptying measured once, early in treatment cannot reveal whether the effect is durable