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The clinical evidence for NAD+ nasal spray specifically is still developing, even though the underlying NAD+ biology is well-established

[2] However, elevated MMA is not conclusive, as it is seen in people with B 12 deficiency, but also in elderly people who have renal insufficiency, [28] and elevated homocysteine is not conclusive, as it is also seen in people with folate deficiency

A seasonal influence has shown that spring pastures have lower levels of trace elements due to faster growth, and lower uptake of elements from the soil