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Conversely, the DSS group exhibited severe mucosal damage, including crypt destruction, depletion of goblet cells, and extensive inflammatory cell infiltration

FIGURE 6 4 Discussion In this study, we reveal the beneficial effects of FOXO4-DRI on aortic vessels under various aging models

Further studies are needed to clarify these points and to elucidate the role of dopaminergic and nondopaminergic pathways in nociception, central modulation of pain and affective/motivational dimensions in the perception of pain